Zyban® (Bupropion SR)

Zyban® is taken in tablet form and is a first line medication for smoking. It is only available by prescription from your physician or pharmacist. The medical ingredient in Zyban is bupropion which can minimize your experience of withdrawal symptoms making quitting easier for you.

Why use Zyban®?

  1. Can double your chances of quitting smoking.
  2. You only take tablets once or twice a day.
  3. You can combine it with counselling support and NRT to improve your success rate in some cases.

Who should not use Zyban®?

  • If you are currently taking Wellbutrin
  • If you have a current seizure disorder
  • If you have a history of eating disorders 

Important! Before starting Zyban, discuss wit your doctor if you have depression or other mental health diagnoses. Also discuss with your doctor your full list of medications as Zyban can interact with other drugs and they may need dose adjustment.

How do you use Zyban®?

  • Set a quit date that is about 1 week after starting the medication
  • Follow the instructions from your doctor and pharmacist
  • Typically Zyban is used as follows:
    • Day 1 to 3: take one 150mg tablet once daily
    • Day 4 to end of treatment: one 150mg tablet twice daily, at least 8 hours apart
  • Swallow the tablets whole. Do not chew, cut, crush or dissolve tablets before taking (as this will destroy the tablet’s sustained release mechanism and can lead to increased side effects) 

Useful-tip: 

Skipping a dose reduces Zyban’s effectiveness. If you do forget a dose do not take two tablets next time to try to make up for the missed dose